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On 04/09/99 Charlie responded to a question about the use of Reglan with PD. His explanation clarified questions I have had about the differences in response to various medications PWPs take, and I have a question about the use of drugs like Reglan or the numerous opiates that interfere with the use of levodopa: If certain drugs "unmask" the symptoms of PD, could a threshold use of such a drug be used to assist in the accurate diagnosis of PD in borderline cases? It took several years of trips to Stanford and all sorts of tests before my husband's wworsening "peripheral neuropathy was finally diagnosed. Martha Rohrer CG for Neal (78/13) [log in to unmask]