Happy Parkinson's Birthday to you. I have been to 1 orthopedist, 2 accupuncturists, 1 chiropractor and my GP for chornic back, knee (both) and hip (both) pain. I started on Pain Free (Clucosoamine 500 & Chrondroitin 400) 1 twice a day plus 1 Ibuprophen 800mg. at nite. No pain or discomfort. I suggest calling Schiff at 1 800 526-6251 to be sure that Pain Free will not interfere with other meds you may be taking if you choose to try it. I am a firm believer in this "joint support formula". Helen Mason RN