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Brian; ( response for my wife, Doris)

1. Which agonist?   -   Permax  ( Neuro wanted to change to Mirapex, but I
persuaded him to stay with Permax. To increase the dosage and to await
entacapone.

2.  When started. -      1997.  A very, very gradual increase in dosage. An
earlier experiment with Permax had proven disastrous because of very rapid
increase in dosage.

3. When diagnosed.  - 1993

4.  Age of diagnosis. -  70

5.  First symptoms.   - 1990

6.  Sinemet intake:  -   5 x 25/100 CR;  2 X 1/2 25/100 R

7.  Dopamine intake.  - 3mg (to be slowly increased to 4)

8.  No,  - But when we asked about increasing he did mention that there are
patients taking far more than she was.

Jules cg for Doris, 76/6