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Hi Brian 1.Requip 2. March 19,1999 3.1997 4.50 5.1993 6.none was taken off Sinemet and Parlodel 7.1mg three times a day 8.no ----- Original Message ----- From: Brian Collins <[log in to unmask]> To: <[log in to unmask]> Sent: Thursday, April 15, 1999 3:43 PM Subject: Sorting out the Agonists > I think it's about time that we got a clear picture of the various dopamine > agonists, since they feature in most people's drug diet these days. For > instance; I take Permax (Pergolide) in addition to levadopa. Over the last > 6 years I have worked myself up from zero to 5 mg of Permax in order to > combat the steady deterioration which is the hallmark of PD. Now this simple > fact is of very little use if I want to see into the future, unless I can > relate my current intake of Permax to some absolute standard. Not only > that, how do I relate my situation to that of someone taking say Ropinirole > (Requip)? With your help, I think we can answer these questions. > > What we need is for as many members of this list as possible to complete the > response form at the end of this e-mail. I have not seen this attempted > before (maybe it can't be done) but let's make the attempt. > > Problem areas: A key question is 'What is the maximum safe dosage of > whatever drug you are using?' This is bound to be a moving feast in > practice: for instance; when I was taking 2 mg of Permax, my neurologist > told me that about 4 mg would be the maximum safe level. When I reached > 4mg , he told me that people were taking up to 12 mg. I am very grateful > to these pioneers for effectively opening-up my future by several years. > > If we get enough of a response to make a useful analysis I will attempt > to do so, and will make the data available to anyone who asks for it. Of > course any results will be published in the list. > > Questions: > > 1/ Which Dopamine Agonist are you taking? > > 2/ When did you start taking it? > > 3/ When were you diagnosed as having PD? > > 4/ What was your age when diagnosed? > > 5/ When do you believe (with hindsight) that you experienced first symptoms? > > 6/ What is your present daily intake of levodopa? (Sinemet, Madopar) > > 7/ What is your present daily intake of Dopamine Agonist? > > 8/ Has your neurologist advised you of the max. safe dose for your agonist? > > > -- > Brian Collins <[log in to unmask]> >