Dear Barb M. - Thanks for the input about Mirapex even if you aren't having to try the agonist /sinimet balancing act right now- We're in process of getting value from an agonist at all and need to know what may be possibilities with Mirapex - the arthritis flare up is interesting , so my husband can know what to watch out for in our journey into uncharted medical waters ( the doctors are great .... but not always the best navigators!) Marie