I would be really interested in hearing about your peripheral neuropathy. I had extensive tests which showed I don't have it. My movement disorder specialist was sure I had it. What are your symptoms and how is it treated? I'm very interested in your experience. Anne Orr at [log in to unmask] ----- Original Message ----- From: James Griffin <[log in to unmask]> To: <[log in to unmask]> Sent: Tuesday, April 20, 1999 10:02 AM Subject: Meals & Sinemet > I read on the list server that someone had been advised to take Sinemet > with meals to reduce nausea. My neurologist advises taking sinemet at > least 1/2 hour before meals. It seems the stomach acids and enzymes > produced by the stomach reduce the absorption of the sinemet. I'm taking > sinemet CR 50/200 twice a day and requip 1 mg 4 times a day. > I'm also taking 10 mg Baclophen 3 times a day for leg cramps. A recent > emg showed peripheral neuropathy in legs. The neurologist says that > neuropathy does not come from PD which I have had for two years.(Age > 71). > Would like any comments on use of baclophen and peripheral neuropathy as > they relate to PD. > Jim