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From: Eldon Green <[log in to unmask]> To: [log in to unmask] Subject: ENTACAPONE ? Date: Thursday, April 22, 1999 10:17 PM Eldon, You are correct. TASMAR is a Roche product which is available in the US and several other countries. TASMAR has received bad publicity recently as a result of side effects. There were at least three fatal events of fulminating liver disease. ENTACAPONE is a similar drug in that it is also a COMT inhibitor. ENTACAPONE, to be known as COMTESS OR COMTAN if approved and marketed, is manufactured by Orion Farma of Espoo, Finland. ENTACAPONE does not appear to cross the blood/brain barrier while TASMAR apparently does. I have been taking ENTACAPONE as a drug trial participant since June, 1994. It appears to have done me no harm to date. It is an effective extender of levodopa, but the same results may be had from use of the controlled release carbidopa/levodopa products already marketed. Will Johnnston A.P.D.A. DelMarVA Chapter Pres. 4049 Oakland School Road Salisbury MD 21804 USA 410-543-0110 I am confused. There is a posting where someone is calling TASMAR entacapone. I have Roche Lab's literature and it is listed as tolcapone. I am under the impression that entacapone is a different drug not yet available in USA. I use Tasmar and the results are well worth the arm stick every two weeks. Eldon Green Tampa Bay Florida