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Linda, I am on Mirapex too and when I increase it ( was taking 6mg a day) I had orthostatic hypotension that was awful. We cut back to 3 mg. a day and it is better. I am further along than you though...14 years. Here are my meds: AM: 1 Sinemet CR; 2 Sinemet 25/100; 1 Mirapex (1mg) NOON: 2 Sinemet 25/100; 1 Mirapex (1mg) PM: 1 Sinemet CR; 2 Sinemet 25/100; 1 Mirapex (1mg) Just don't let it get too bad. Mine was as low as 87/36 - 99/45 and so on. Jeana 46/14/33