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It is interesting to find someone with this same problem. Mine is just the same but opposite side. I get double vision and bluriness when my eyes get tired but the closing of my left eye, happens when I am tired but also, always when I am off. Have you had any explanation for your problem. Only thing I have been told is that the closing of the eye is connected to the sixth cranial nerve. Whatever that means. No explanation about the dialation and asymetry of the pupils. Thanks for your response. Jennifer Smith B & N Nothnagel wrote: > this is in responce to jennifer smith: i also have had the pupils of my > eyes dilate to different sizes. it isn't all the time and pd-(msa) is > more prominant on my right side and that eye dilates less than the left > side. also, when i am tired i can't keep my right eye open. so far i > do not have double vision.