-----Oorspronkelijk bericht-----
Van: Camilla Flintermann <[log in to unmask]>
Aan: [log in to unmask] <[log in to unmask]>
Datum: vrijdag 30 april 1999 19:40
Onderwerp: Medications publication
Hi Camilla,
>> Recently there have been a couple of questions on the PD internet
discussion list about the drug Buspar. PWPs have been told it is
contraindicated for PD. <<
Here is a summary on the use of Buspirone with some indications why it
better can be avoided if possible by PWP. Deviding the interference of other
meds with PD or PD-meds into the categories LOW, MEDIUM and HIGH, the med
Buspirone is in the LOW category.
Hans.
BUSPIRONE
Some commonly used brand names are:
In the U.S.: BuSpar
In Canada: BuSpar Bustab
Category: Antianxiety agent
Description
Buspirone is used to treat certain anxiety disorders or to relieve the
symptoms of anxiety. However, buspirone
usually is not used for anxiety or tension caused by the stress of everyday
life.
It is not known exactly how buspirone works to relieve the symptoms of
anxiety. Buspirone is thought to work by DECREASING the amount and actions
of a chemical known as SEROTONIN in certain parts of the brain.
Before Using This Medicine:
In deciding to use a medicine, the risks of taking the medicine must be
weighed against the good it will do. This is a decision you and your doctor
will make. For buspirone, the following should be considered:
Older adults: This medicine has been tested in a limited number of older
adults and has not been shown to cause different side effects or problems in
older people than it does in younger adults.
Other medicines: When you are taking buspirone, it is especially important
that your health care professional know if you are taking any of the
following:
- Erythromycin (e.g., ERYC, E.E.S.) or Itraconazole (e.g., Sporanox): Higher
blood levels of buspirone may occur, increasing the chance of side effects.
Your doctor may change the dose of buspirone that you take.
- Monoamine oxidase (MAO) inhibitors (furazolidone [e.g., Furoxone],
phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegiline at
doses MORE than 10 mg a day [e.g., Eldepryl], tranylcypromine [e.g.,
Parnate]): Taking buspirone while you are taking monoamine oxidase (MAO)
inhibitors may cause high blood pressure.
Precautions While Using This Medicine:
Buspirone may cause some people to become dizzy, lightheaded, drowsy, or
less alert than they are normally.
Side Effects of This Medicine:
Rare: Chest pain; confusion; fast or pounding heartbeat; fever;
incoordination; mental depression; muscle weakness; numbness, tingling,
pain, or weakness in hands or feet; skin rash or hives; stiffness of arms or
legs; sore throat; uncontrolled movements of the body.
Symptoms of overdose:
(may be more severe than side effects seen at regular doses or several may
occur together)
Dizziness or lightheadedness; drowsiness (severe) or loss of consciousness;
stomach upset, including nausea or vomiting; very small pupils of the eyes
Other side effects may occur that usually do not need medical attention.
These side effects may go away during treatment as your body adjusts to the
medicine. However, check with your doctor if any of the following side
effects continue or are bothersome:
More common: Dizziness or lightheadedness, especially when GETTING
UP FROM A SITTING OR LYING POSITION; headache; nausea; restlessness,
nervousness, or unusual excitement.
Less common or rare: Blurred vision; clamminess or sweating;
decreased concentration; diarrhea; drowsiness (more common with doses of
more than 20 mg per day); dryness of mouth; muscle pain, spasms, cramps, or
stiffness; ringing in the ears; trouble in sleeping, nightmares, or vivid
dreams; unusual tiredness or weakness.
(Revised: 03/17/98)
