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Ed:  Two experiences my husband has had in the past l2 yr - l.  Started on
cogentin
for tremor (only med. for two years) and tried to reduce when began Sinimet
but he
still takes 2X.5mg/day - when he tries to not take any his tremors increase-
other-
wise no problem with tremors.  2.  He's always taken meds spread evenly over
a
24 hr. period.  Takes middle of night dose when gets up for bathroom anyway -
about 2 A.M. give or take 1 hr.  The interruption is well worth the benefits
and he has had very few episodes of disturbing cramps or rigidity.  He tried
to take a daily
schedule ( as recommended by the Dr.) three times, always with poor results -
so
we stay with the tried and true method.
                     Just a couple things to consider - hope things go better
for Jack ,
whatever, you decide to do.....               Marie     Carepartner for
husband 69/l2