Judith (and others): I have been taking Sinamet 25/100 three times a day for month --since being diagnosed with PD. As you may recall (from earlier posts), my first few days were rough (no titration) and I experienced a lot of side effects. My neurologist was at the recent conference in Toronto. From this meeting, and since I am early onset, he recommends that I switch to just Mirapex at 0.5 mg. three times a day. He recommended phasing out the Sinamet over a few days. Should I ease into the Mirapex also? I'm going to try to ease into this transtion...any suggestions? ............................................................................................ Ray Strand mailto:[log in to unmask] ............................................................................................ ...on the edge of the prairie abyss ......................