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> --make drug changes gradually (here called titration) > In this case, I believe that titration means to give just the right amount of drug enough to obtain a desired reaction from the patient. Patients vary in size, weight, advance level of the disease, etc. so that each may need different amounts of therapeutic drug. In chemistry from where this term is taken, a typical example of a titration is adding just the right amount of acid to neutralize a base. Michel Margosis