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SMACK!! <-- Bard smacks Ivan upside his wee head) You just HAD to go and mention ICE CREAM didn't you!?! (mouth watering) <grinning> NOW I'll be thinkin' about ice cream ALL day.... no... make that all WEEKEND! I wonder if one can gain weight from excessive THINKING about ice cream.... <LOL> Barb Mallut] [log in to unmask] -----Original Message----- From: Ivan M Suzman <[log in to unmask]> To: [log in to unmask] <[log in to unmask]> Date: Friday, May 07, 1999 11:47 PM Subject: Re: On the trail of the cure: the PWP sugar puzzle/ a GENE? >Jennifer and the million other PWP's who crave sweets--not to mention ICE >CREAM - did I say that? --: > >Could a single GENE, if mutated, shut down the dopamine to adrenaline >pathway, and cause a variety of different diseases, including PD or >diabetes? Could this explain why there seem to be many more diabetics >within the families of PWP's than usual? > >Are any of the PD foundations and societies, American or overseas, >looking into this? Robin Elliot, Carole Cassidy, Ida Kamphuis, Brian >Collins, Perry Cohen, Parkinson's Alliance, NPF, APDA, other >countries--what do you think? > >Any biochemists or geneticists out there wish to respond? > >Thank you, > >Ivan > >On Fri, 7 May 1999 17:06:06 -0400 Jennifer Smith <[log in to unmask]> >writes: >I plan to pass the info >onto my>friend who asked me the question about >sugar cravings and PD. >>Jennifer Smith >> >>Ivan M Suzman wrote: >> >>> ^^^^^^ WARM GREETINGS FROM ^^^^^^^^^^^^ :-) >>> Ivan Suzman 49/39/36 [log in to unmask] :-) >>> Portland, Maine land of lighthouses 64 deg. F :-) >>> ****************************************************************** ** >>> Hello again, folks, >>> >>> Here's a thought, ESPECIALLY if you have discovered that you need >>extra >>> SUGAR at times: >>> >>> PD is caused by lowered dopamine. Dopamine breaks down to >>adrenaline; >>> so I wonder if dopamine deficiency in PWP's means lowered adrenaline >>in >>> those PWP's, too. >>> >>> Adrenaline, meanwhile, inhibits insulin. So, I also wonder if >>lowered >>> adrenaline could leave insulin production less regulated, resulting >>in >>> excessive insulin in PWP's. >>> >>> Raised insulin lowers blood sugar. Could this explain a PWP's >>need for >>> sugary foods and sweets, which we often talk about here on this >>list, to >>> compensate? >>> >>> "Hypoglycemia" is low blood sugar. A neurologist I talked to says >>that >>> lowered blood sugar symptoms--shaking muscles, cold sweat, >>exhaustion, >>> tremor -- are very similar to lowered dopamine symptoms that appear >>> either before dose, or with end of dose off-periods of PWP's . >>> >>> One last thought for now --does lowered adrenaline give you that >>BLAH >>> feeling (no motiviation to do anything because you just DON'T have >>the >>> energy? >