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On Sun 23 May, Teresa V. Bohuszewicz wrote: > Can anyone help with this question? > > Teresa > > -----Original Message----- > From: RAJ BANDEKAR [mailto:[log in to unmask]] > Sent: Thursday, May 20, 1999 8:00 PM > To: Public Discussions Forum > Subject: Bromocryptine Drug Information > > My father age 77, is suffering from Parkinsons disease for last 9 years. He > has been on Syndopa (a.k.a levadopa), eldepryl and pacetone drugs. His > Parkinsons was under control till about past 6 months. Now it appears to be > getting a little more severe. His doctor told us that the above drugs are > having lesser effect now. Therefore he has suggested to introduce a new > drug Bromocryptine. Has anybody heard about/have any first or second hand > experience with this drug? I am interested in knowing if there are any side > effects, how strong the drug is etc. > > I would appreciate any help. > > Thanks a lot > > Raj Bandekar. For RAJ BANDEKAR Hello Raj: RE: Bromocryptine, also known as PARLODEL. This was the first of the Dopamine agonists to be put on the market, at a rough guess about 10 yrs ago. It was added to my drug list as I was in considerable trouble trying to cope with l-dopa alone. Let me say first that I am sure that there are many people out there who are getting satisfactory results taking Bromocryptine. However, I am not one of them!! I found that after about 6 months on the drug, I began to become neurotic - I gave my wife a very hard time, Argued all the time, and generally was a pain in the ***. Fortunately a friend managed to gather the courage to tell me what I was doing, and I dropped the bromo immediately. 2 weeks later, I was my old self. I have seen enough comments from other PWPs to convince me that the risk of unpleasant side-effects from Bromo is significant. Another important point is that the later agonists claim to have the ability to substitute for some of the levadopa, without provoking the associated dyskinesias (Random unco-ordinated ordinated movements of the arms, legs, or somtimes the whole body. If you see words like 'stimulates the D2 receptors only' they will be referring to the above point. Drug companies like to claim that their product is ,'neuro-protective' meaning that they (as a supplementary function) fight against the (still unknown) causes of PD. I do not believe that any of them have this property In summary; there are more effective drugs on the market, with lower (but not zero) chance of side-effects. I would suggest that your advisor should drag himself into the 20th century -- Brian Collins <[log in to unmask]