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On Thu 27 May, Jim Finn wrote: > Group - > > Here's a little trick that I find helps to quickly "kick-in" Sinemet; > especially the first dose in the morning. > > Instead of taking it with water, I use regular (Classic) Coca-Cola. It seems > (for me, at least) to work better than water or fruit juice. > > Try it; you've got nothing to lose. > > Jim > > > Hello Jim, This kind of practical assistance to those less experienced in using Sinemet is good to see; If you don't mind, I would like to add it to the next revision of my 'Living with Levadopa' booklet. while we are on the subject let me warn those who take a much higher dose than normal first thing in the morning, in a desperate effort to get themselves up and running. I understand the need, and yes, you do arrive at the target rate of flow earlier if you take a larger dose, BUT from that point on, you start to pay for that high dose - You go shooting through the the target rate of flow, into an area where I am convinced is not a good place to be. You may not sufeer any noticeable effects, but this may be because you are on the 'learner slopes' of PD, and damage may still be occuring, and will show up in later stages of PD Regards, -- Brian Collins <[log in to unmask]>