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On Thu 10 Jun, Callie M. Judd wrote: > The main change we are attempting right now is to remove the > Cogentin from > his mix altogether, since he has been on it for over l2 years and is down to > lmg/day. > Am I right in my perceptions that "tremor" is distinctly different from > "dyskinsia"? > The "pill rolling tremor " he has had since day one, and the Cogentin has > always > effectively eliminated it from being a problem- but about four years ago he > started > experiencing a "rolling" in his legs and jaw that seems to be a dyskinesia I > finally > found out (on our own, as usual) could be a result of long term Sinimet > usage. He > had been on Sinimet st for about 7 yrs when it first showed up and the Neuro > in > Arkansas agreed to prescribe Sinimet CR for him (at our inquiry about it). > He's been on CR for about 4 years now but the intermittent episodes are > gradually being > more of a problem to him so we requested an agonist which is how we got the > Bromocriptine prescribed. We're up to 20mg/day now and things aren't > changing > much. Perhaps we do need to "fine tune" the Sinimet but I've been reluctant > to do > too much changing too fast. Any suggestions anyone can give will be greatly > appreciated since few definitive answers ever come from the Dr. and the last > time > we saw him he put our appointment interval to a six month rather than a 3 > month > time so we don't see him until Aug. again. > The last reduction we tried of Sinimet (to 600mg/day) resulted in > what we > think was a sever episode of dystonia. So we keep muddling on........ > By the way, I hope I told Joao, in Brazil, right , that you had done > the survey > on Agonists a while back? I'm subject to remember wrong and things are so > "busy" around here lately, I didn't take time to research it before I said > it.......I want > to interact with the list more, but been lurking mostly lately, and staying > behind..... > Thanks - > Marie in Texas > > > Hello Marie, I sympathise with you trying to understand what is going on. One of your problems is I think that you attribute too much to the drugs. I do not believe that different drugs affect different symptoms - it doesn't work like that. Imagine all your PD symptoms stacked-up in the order of how much Sinemet it takes to affect them. This is how it is: anyone else will probably have different symptoms, or the same symptoms stacked up in a different order. Either way, their results will be irrelevant to you. I hope you get on OK with Bromocryptine. I don't like it myself (Bad psychological side effects) And it is not selective in which dopamine receptors it stimulates, unlike the later Agonists. I get on well with Permax myself. I start a 2-week vacation tomorrow, I am stopping my mail, so if you call me, use my personal address, then I will have a record when I return, Regards -- Brian Collins <[log in to unmask]>