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Dear Rosemary, Yes this has happened to me many many times. I am 38 years old and have had pd since the age of 20. I am now on Liquid Sinemet and have to take sips of it off and on all during the night. If I go too long without a sip of sinemet..I will literally freeze. It is extremely hard for me to call out, or roll over, or even to raise up from the bed. I keep my Liquid Sinemet as close to me as possible. If it has been a tough day for me I will even keep the bottle in the bed with me.. I hope this has helped. Sandra 39/dx'd 28/onset 20