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Thanks to those who confirmed the URL for the archives site. However, for some reason I still can't access it. So I will ask on the list about Zoloft. I read in a pain management book that anti-depressants have analgesic qualities. Since my husband has been in constant pain since his (non PD) surgery 8 months ago, and has naturally become depressed about it, I thought it might be worth a try. I believe Zoloft is an SSRI, the only family of anti-depressants that is safe for a PWP to take. Please tell me what your experiences with this med have been. The pain management book says anti-depressants have analgesic (pain relieving) capabilities even for the non-depressed. Interesting. Ann Gibbons cg Joe 65/2