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From what I've read, I think CoQ10 works by giving energy to the mitochondria in our cells. Or it could be that they help the mitochondria to do it themselves. Anyway, I recently saw a book at Barnes & Noble that I want to go back and get. It's called, "Brain Wellness Plan." They have a whole chapter dedicated to PD, whicih is ofen hard to find. In it, they recommend various supplements to aid with pd and two of them are the NADH and CoQ10. They had other ones too, but I don't recall what specifically. It looked like a pretty good book. The authors were Dr. Jay Lombard and Carl Germano, and the isbn number for anyone who wants it is 1-57566-293-0. Oh, I forget where I ran across this Taoist proverb, but it is certianly appropriate here: "When you have a disease, do not try to cure it. Find your center and you will be healed." For those who are more traditional Christian (they're both the same to me) the corresponding scripture would be the one "Seek ye first the Kingdom of God (i.e., within yourself) and all these things shall be given you. That's exactly how I feel about this pd stuff. If I focus on pursuing my purpose I will be given everything I need, and that includes eventually being healed/cured, just as a byproduct. Once it's no longer needed, it'll go away of its own accord. Wendy Tebay