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Clare, Sorry about mis-spelling Clare in my e-mail to you last time. I thought I was seeing a movement speclialist, Dr. Hubble at OSU Medical center. She keeps trying different meds. I'm taking Sinemet CR(2), Permax(6),150 mg of zoloft, and HRT once a day. The trouble is I don't know if my feelings are a normal progression of the disease or the meds or lack of. My tremor has been stopped but freezing and stiffness are my constant companions. Shouldn't the medicene do more or is that wistful thinkng? Patricia 62/5 years