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I have taken zoloft since I was diagnosed. I take the following PD drugs: Sinemet, Premax, Eldepryl--some say this is counteridicated but my neuro says its ok-- and Mirapex. I have not noted any analgesic qualities, but not sure that I would recognize them. I do feel rather cheery most of the time, and credit the Zoloft when I realize I have been trying to do a button for 10 moinutes without getting upset. Nancy Shlaes deGrazia (62/57) MR JOSEPH GIBBONS wrote: > Thanks to those who confirmed the URL for the archives site. However, > for some reason I still can't access it. So I will ask on the list > about Zoloft. I read in a pain management book that anti-depressants > have analgesic qualities. Since my husband has been in constant pain > since his (non PD) surgery 8 months ago, and has naturally become > depressed about it, I thought it might be worth a try. I believe > Zoloft is an SSRI, the only family of anti-depressants that is safe > for a PWP to take. Please tell me what your experiences with this med > have been. The pain management book says anti-depressants have > analgesic (pain relieving) capabilities even for the non-depressed. > Interesting. > > Ann Gibbons cg Joe 65/2