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Hi Brian, Just wanted you to know that so far Artane is the ONLY medication that has helped my husbands tremors of his arm only. His side effect is sometimes nausea. He has tried Mirapex and had severe hallucinations. He tried Sinemet and had no change except he had no desire to eat at all. Everyone is different He also tried Requip with no change except nausea and confusion. So far none of the new meds has helped him. He is trying to find something for the constant tremor in his face and jaw with no success. Sincerely, Rose