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hi all my fingers are sore from digging through nine million abstracts at PubMed but i found the two countem two abstracts which matched the query terms: levodopa short term response and levodopa long term response the one on dystonia is not specifically directed at PD [they mention a 'holiday' from levodopa - what a misnomer!] the one on pharmacokinetics is dated 1990 pretty old in pd medication terms still mulling... janet janet paterson 52 now / 41 dx / 37 onset PO Box 171 Almonte Ontario K0A 1A0 Canada a new voice <http://www.geocities.com/SoHo/Village/6263/> [log in to unmask]