Janet, et al.... I've heard several different movement disorder specialists speak over the past 5 years and a number of them have suggested if one's having bad side effects from their Sinemet to pop the tablet (or 1/2 tablet) under their tongue, let it "melt there," and then swollow. Tho I've never taken my daily Sinemet that way, I know a few PWPs who will ONLY ingest it by "melting" it first 'cause they have - like yourself - a MUCH more beneficial response that way, Barb Mallut [log in to unmask] ----Original Message----- From: janet paterson <[log in to unmask]> To: [log in to unmask] <[log in to unmask]> Date: Tuesday, July 06, 1999 7:03 PM Subject: cure / good med management / melting sinemet cr >hi all > >there's been a lot of discussion >about finding and funding the Cure lately > >there was a post recently >about someone who's managed pd quite well for 25 years > >i've had pd for 14-15 years >i've been on sinemet for 11 years >and i've discovered something new about my med 'management' > >i have avoided sinemet cr like the plague >because it tends to give me dyskinesia and dyspepsia >[not a pretty sight] > >i have generally stuck to >half 10/100 sinemets every 90 minutes or so >and have had generally good 'coverage' as a result >the only real flaw in the ointment seemed to be eating food [!] > >for some unknown reason a couple of weeks ago >i decided to try 'melting' a half 25/100 sinemet cr in my mouth >rather than swallowing it whole >[i didn't care about the time-release factors being wasted] > >has anyone else tried this approach with cr? > >i'm quite pleased and surprised by the results so far > >i have pretty much replaced >about half of my daily sinemet with sinemet cr > >no dyskinesia and no dyspepsia >hah! > >and a trace of the time release capability seems to be still available >since my "ons" and "offs" are 'gentler' and slower now >hah! > >and having something to eat does not seem to interfere >with the subsequent dose as much >hah! > >right now i am enjoying a long smooth "on" >the best in months or even a year or two >slightly twitchy toes is all >virtually identical to >pre-pd > >it just occured to me >if the cure isn't found for a few years >good med and symptom management is as good as being there > >and is as much of a miracle as a cure would be >imho > > >janet > >janet paterson >52 now / 41 dx / 37 onset >snail-mail: PO Box 171 Almonte Ontario K0A 1A0 Canada >website: a new voice <http://www.geocities.com/SoHo/Village/6263/> >e-mail: <[log in to unmask]>