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Patsy.... I've taken Coenzyme CQ10 for nearly a year. I find my energy lever is higher (not a lot higher, but none the less noticeably higher) The CQ10 has also been VERY beneficial in keeping my gums healthy (Dentists who are on the ball know of CQ10's positive effect on the gums but older, more traditional ones don't seem to have a clue). Initially I had no idea how much CQ10 was the proper dose to take without over dosing or underdosing. Certainly there was no mention on the label of a suggested dosage. Finally I called a clinical pharmacist I'm acquainted with and asked him what be an AVERAGE dose of the CQ10, and he suggested 300 mg. per day. The strongest dose I could find locally has been 75 mg. tablets, 30 to a bottle. They are VERY costly when purchased directly from the drugstore. I take the CQ10 along with my A.M. Sinemet and the late afternoon Sinemet. This is a personal choice (i.e., read that as "easist") as there's no specific directions on how often the CQ10 should be taken throughout the day. Personally, I don't believe - or can't see in my own body - the CQ10 does anything positive OR negative in reqards to PD. It MAY actually be a wonderdul benefit to others with PD, but in my own case I can notice no change in the Parkinson's one way or another. Barb Mallut [log in to unmask] -----Original Message----- From: Jerry Manning <[log in to unmask]> To: [log in to unmask] <[log in to unmask]> Date: Tuesday, July 13, 1999 5:09 PM Subject: coenzyme Q10 and NADH >Dear PWP, > >Are any of you out there taking coenzyme Q10 or NADH? and if you are how >much are you taking, and when do you take it .....along with your regular >meds for PD? or at a separate time during the day? Has anyone out there >benefited by taking either of these supplements and if so how? And, has >anyone been able to lower their sinemet intake due to taking either >coenzyme Q10 or NADH? > > If anyone has any info about either of these ie. research being done with >either? >articles that anyone has read related to these? any info at all, I would >be so interested in hearing from you. > > One more thing.....I recently read that sinemet loses its effectiveness in >temperatures of 80 degrees Fahrenheit or more. In this heat has anyone >noticed this happening ? and should we store our sinemet in the refrig if >this is the case? > >thank you! thank you! > >Patsy Manning (age 53, diagnosed at age 42, symptoms began when I was 39)