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Hi Janet,

I think that what they are trying (obtusely to be sure) to say is that A
acts as an intermediary for or (controls)B.
It is so obtuse that I am not sure what they are trying to say except
that A is involved in controlling B.

Charlie
janet paterson wrote:

> hi all
>
> At 08:59 1999/07/10 -0500, charlie wrote, in part:
> >I think in standard medical-scientific usage "MEDIATES" does not
> >mean "reduces". It means to be in the middle position or to be
> >a "medium" for bringing about a result...
>
> rats!
>
> if i edit out the multi-syllabic names for simplicity,
>
> where "A" is substituted for
> "a caspase 3 inhibitor,
> acetyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic aldehyde"
>
> and "B" is substituted for
> "an endogenous neurotoxin, N-methyl(R)salsolinol"
>
> the study's conclusion statement reads:
>
> >These results demonstrate
> >that "A" mediates apoptosis induced by "B",
> >which may cause apoptotic cell death of dopamine neurons
> >in Parkinson's disease.
>
> what does "mediates" mean in this context?
> is the wording obtuse or am i?
>
> janet
>
> janet paterson
> 52 now / 41 dx / 37 onset
> snail-mail: PO Box 171  Almonte  Ontario  K0A 1A0  Canada
> website: a new voice <http://www.geocities.com/SoHo/Village/6263/>
> e-mail: <[log in to unmask]>

--
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Charles T. Meyer,  M.D.
Middleton (Madison), Wisconsin
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