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About 1 1/2 years ago my neurologist put me on mirapex( also take eldepyrl and amantadine About 18 months ago my neurologist put me on mirapex(also take eldepyrl and amantadine) and discontinued sinemet cr. i has worked very well for me. I have very little shaking on my right side and no dyskenesia. I take all of my medications on an empty stomach. many can't do that. You might want to give it a whirl. works for me. best regards Murph Brown 57/9