Hi all, Does anyone know what Quality Control tolerances are applied during the production runs of the meds' that we take? The reason I ask is that on several occasions recently I have experienced severely delayed "kick-in" of Madopar, which I normally have few problems with so long as I stick to the same dosing regime. Having worked in a Quality Control environement for Coca-Cola and Scweppes soft drinks who apply strict tolerances on both the volume and strength of their products, I know from experience that problems with " out of spec' " product do happen, especially at the start and end of production runs, and despite the best efforts of the Quality control departments some of these below standard products ocasionally escape the net and reach the consumer. Do the same problems exist in the production runs of Drugs? Could my delayed "kick-in" be due to a sub-standard batch of Madopar capsules? or should I be looking elsewhere for the cause of the problem? Regards, Nigel, 44/11 Taking....Madopar, Cabaser, Eldepryl, Amantadine, Amitryptiline