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Prior to my right side pallidotomy in Deember 1993, I was on 14 Sinemet CR 200/50 and 6 permax 1 mg per day. After the pallidotmy I was down to 9 CRs and 4 permax. After left side DBS of the globus pallidus and STN in Dec 94 - I was the first North American patient to have this procedure - I am down to 4 CRs a day and 2 permax. My stimulator is a Medtronic Extrel model 1425, settings are 10 volts, 220 hertz and pulse width of 200, unchanged since hookup. My energy level is high on a sustained basis since DBS ; I have experienced no problems and have not had an off period since hookup Hope this helps Bill