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Message-ID: <[log in to unmask]> Date: Sun, 18 Jul 1999 10:09:15 -0700 From: "J. R. Bruman" <[log in to unmask]> Reply-To: [log in to unmask] X-Mailer: Mozilla 3.0C-NC320 (Win95; U) MIME-Version: 1.0 To: Parkinson's Information Exchange <[log in to unmask]> Subject: Re: carbon Monoxide and PD References: <[log in to unmask]> Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit Carole Hercun wrote: > > I was > > > exposed to carbon monoxide as a young child, and > > > nearly died from it. Does anyone know of any > > > literature relating to PD and CO. Carole H. A search of PubMed turned up 45 citations, of which 3 are in English and right to the point; PMID 3690934, 7073551, and 4020369. The gist is that CO does induce genuine parkinsonism, as proven by lesions found in the globus pallidus. It seems unresponsive to levodopa (Sinemet) treatment but the agonist bromocriptine (Parlodel) with or without the Sinemet was mentioned as helpful. Cheers, Joe -- J. R. Bruman (818) 789-3694 3527 Cody Road Sherman Oaks, CA 91403-5013