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Sherilyn Sherry wrote: > > Thanks Carole. It seems like when I take more sinemet or miripex the > dysken..(sp) is terrible. Maybe a second opinion is in order. > > My husband travels a lot, my three children are out of town, I'm > feeling lonely and scared I'm pleased to see so many replies from other listmembers to your anxious question- FWIW, here's mine: Sinemet and Mirapex accomplish the same basic effect in two different ways, that is either to replace the dopamine that is missing in PD or to act like dopamine so as to fool the brain cells. Problem with Sinemet is, a dose doesn't last long and you get dyskinesia if you take too much at once. Solution is to take smaller doses but more often, to get the same total amount prescribed (always ask your neurologist first, before making any change). For example if you now take a 25/100 Sinemet every 6 hours, try half a pill every 3 hours instead. Cheers, Joe -- J. R. Bruman (818) 789-3694 3527 Cody Road Sherman Oaks, CA 91403-5013