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Hi all, This may seem like a silly question but I'm trying to learn all I can. So, who better to ask than you, the experts! My mother just recently began taking Sinemet, I wrote to you asking about the nausea problem before. She is taking the 50/200 dosage, she asked her doctor about cutting the pill in half and he said "no" that it isn't the dosage of the med making her sick but just the "nature" of the medicine. The silly part of the question is can a controlled release pill be cut in half (someone told her that you shouldn't) and if you do cut it in half does it become the 25/100 dosage? What she would like to do is start out gradually with this medication. She has been managing on Segeline alone for years but there is no doubt it's time to begin the Sinemet. The trembling and stiffness is becoming worse and balance was starting to become affected. So, we aren't arguing about that. But, since it is questionable how long you can use this medication, shouldn't you start out with the lowest dose possible? Half a pill does ease her symptoms but it really doesn't have much of an effect on the nausea and just an overall "not right" feeling. Still, she would feel more comfortable taking the least amount possible. One more thing, what is a Movement Disorder Specialist, is it different than a neurologist? Thanks again and best wishes to all, Marcia