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Carol, The variability from batch to batch of the name brand stuff can vary as much or more than the variation between the generic and the name brand stuff. I have found more variation in Sinemet than in the generic equivalent from TEVA. Will Johnnston A.P.D.A. DelMarVA Chapter Pres. 4049 Oakland School Road Salisbury MD 21804 USA 410-543-0110 ---------- From: carolmtn <[log in to unmask]> To: [log in to unmask] Subject: DRUG SPECIFICATIONS Date: Monday, July 19, 1999 1:05 AM To Nigel: My name is Carol Walton and I am a member of the Parkinson Alliance Executive Committee--I am usually silent on the listserv but I am catching up on e-mail having just returned from the East--I was told by one of the drug companies that there can be at 20% difference --plus or minus--when different companies make generic drugs--therefore you could be taking a brand name drug--switch to a generic and have a 40% difference--some companies and now trying to set a standard since this can be devastating especially with Parkinsons medications--I hope some others answer you also since I am not an expert in any way shape or form--but I hope this helps and you might run this by your pharmacist--good luck--carol walton