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Cannabinoid receptor binding in the substantia nigra of MPTP-lesioned macaques displaying L- dopa-induced dyskinesia Primates with apomorphine-induced dyskinesias have reduced binding of the cannabinoid receptor antagonist SR141716A in the substantia nigra pars compacta, according to this report. Binding was reduced 30% compared to lesioned non-dyskinetic animals. No significant changes were seen in the pallidum or striatum. MB O'Byrne, C Kobylecki, AR Crossman, JM Brotchie P-MO-147 Parkinsonism and Related Disorders, Volume 5 Supplement, 1999 <http://www.wemove.org> janet paterson 52 now / 41 dx / 37 onset snail-mail: PO Box 171 Almonte Ontario K0A 1A0 Canada website: a new voice <http://www.geocities.com/SoHo/Village/6263/> e-mail: <[log in to unmask]>