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Marijuana chewing-induced improvements in Parkinson's disease This case report documents motor improvements from daily chewing of a single marijuana leaf in a 72- year-old man with Parkinson's disease. The patient was taking 400 mg levodopa/day when he began on marijuana, and continued his levodopa dose unchanged. After two months, he reported improved tremor and bradykinesia. He has continued for five years, with loss of benefit during two treatment suspension periods, and regain of benefit with recommencement of treatment. The author notes the patient has an unusually benign course of PD, that marijuana leaves have a different concentration and distribution of active ingredients than marijuana flowers, and that chewing is likely to produce different effects than smoking. E Ruzicka P-TU-136 Parkinsonism and Related Disorders, Volume 5 Supplement, 1999 <http://www.wemove.org> janet paterson 52 now / 41 dx / 37 onset snail-mail: PO Box 171 Almonte Ontario K0A 1A0 Canada website: a new voice <http://www.geocities.com/SoHo/Village/6263/> e-mail: <[log in to unmask]>