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> I've only seen it twice in fifteen years as a
> Psych-Mental nurse, but here goes. The patient starts
> running a high fever, becomes delirious (which is
> difficult to distinguish from psychosis),becomes very
> rigid, and appears very ill, with elevated vital
> signs, etc. It is somewhat rare and very complicated.
> Best description of NMS I've come across is the
> University of Iowa's VIRTUAL HOSPITAL'S "Clinical
> Pharmacology Seminar 1996-1997", which is extremely
> informative:

Another (rare) complication of neuroleptic malignant syndrome is
when the myoglobin in the muscles (which are in severe spasm)
breaks down and gets out into the bloodstream.  It turns the urine red
(looks like blood but isn't) and eventually can clog the kidney tubules
causing kidney failure.  In such cases, dialysis may be necessary.

Neuroleptics are dangerous drugs.  They have some uses in severe
psychosis, but not in other conditions.  The "newer" ones like
Risperidal are reputed to have fewer side-effects, but I don't believe it,
having seen some pretty bad reactions from such drugs, especially in
older people.


Best,

Bob


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Robert A. Fink, M. D., F.A.C.S., P. C.
2500 Milvia Street  Suite 222
Berkeley, California  94704-2636
Telephone:  510-849-2555   FAX:  510-849-2557
WWW:  <http://www.dovecom.com/rafink/>

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