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I take selenium 200 mg and ginsana sport as well as One A Day for Men, all once a day + sinemet 25/100 (4 or 5 times a day), mirapex 1.5 mg (2x a day) and tasmar 200 mg (2 or 3 times a day), I don't know how much the selenium, the Ginsana Sport, and the multi-vitamin help, but I believe they do. I keep a law firm running during the day. Hope this helps. Harlan Williams, Jr. Williams International Patent and Trademark Office www.williamspatent.com