 |
 |
thx to all those who wrote tohelp me open the newsletter..here's the part on dopamine hci. Joan DOPAMINE HCl in 5% Injection in Flexible Containers [June 5, 1999: Abbott] PRECAUTIONS: Weaning: Subsection revised (new text in italics) - "When discontinuing the infusion, it may be necessary to gradually decrease the dose of dopamine HCl while expanding blood volume with IV fluids.["since" deleted] Sudden cessation may result in marked hypotension." Geriatric Use: (new subsection) - "Clinical studies of dopamine injection did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy. DOSAGE AND ADMINISTRATION: Rate of Administration: Sentence added at end of subsection: "When discontinuing the infusion, it may be necessary to gradually decrease the dose of dopamine HCl while expanding the blood volume with IV fluids to prevent the development of marked hypotension."