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hi all At 07:04 1999/08/19 EDT, renee wrote: >Hi all. I haven't read all my email, so the info I'm about to put forth may >already be there, but here goes: my mother (75, PD for 12 years) has started >(about 3 weeks ago) taking Sinemet 25/250 in liquid form on an hourly basis. >She mixes all the day's Sinemet and 1000 mg of Vit. C in one quart of water >and blends it in the blender. Then she drinks between 2 and 3 ounces every >hour for the rest of the day. Aside from the major inconvenience of the >"therapy" and the fact the she has to wear an improvised "timer" around her >neck ( also she is slighly hard of hearing), she is much improved. The ups >and downs of taking Sinemet in pill form are much much smoother and she has >no more totally "off" times. She has also decreased the Eldepryl by 50% (I >can't remember the exact dose at this instant). >Does anyone have any experience with something like this? Please send >feedback. Thanks. Renee renee, that sounds great! and just as one might expect as pd [along with sensitivity to levodopa] progresses the "window" for optimum response to levodopa gets narrower and fine-tuning for reducing under- and over- medicated states becomes a primary issue thus, timing becomes critical maybe once your mother starts enjoying the smoother ride she'll come to look on the daily med preparation as less of a chore in re the timer, maybe an alternative with a vibrating alarm rather than a sound alarm could be found? janet