 |
 |
Bonnie R. asked: > What does Mirapex do different from the Sinemet? > As far as I know, Mirapex (generically pramipexole) is an agonist like Permax, Parlodel, Tasmar, Requip, and Comtan. The agonist mimics the action of Sinemet which is called the gold standard for treatment of PD. According to my understanding of the pharmacology of this system, it reduces the freezing periods and smoothes the transition between the "on's" and "off's". Yet, because each individual is unique, some drugs work better than others. I could try to seek out the technical text of the drug monograph, but that would become very complex gobble de... Michel