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Rayna - I think Joan Samuelson is overstating the case. When she says "unable to...", read "has difficulty with." That would be more accurate. It takes many years to get to that point, and for many, there are surgical solutions which offer a new lease on life. For a PWP in the early stages, there's reason to hope an actual cure will be found in time to benefit them. If it helps, I can tell you that my husband's neuro, a well-respected movement disorder specialist, recently moved to Florida to involve himself in the search for a cure. He said before he left that he believes the cure will be found within five years. Margie cg for Dick, 54/17 << As someone with a spouse in stage 2 with a tremor on one side being pretty well controlled with 2-/1/2 sinemet 25/100 per day, I found this article totally depressing. Is this what we have to look forward to? Rayna >>