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Dimethylamine passes through the skin. It meets melanin and inhibits it by using it to form an indole (Ethoxyquin). This indole crosslinks with methylglycoxal. You will find this crosslinking in Parkinsons, Diabetes II, and Psoriasis. It then binds with a multidrug resistant P glycoprotein that carries it across the blood brain barrier. It binds with metallic ions, so it binds with the iron in the substantia nigra increasing the diiron complex AAT that is high in Parkinsons and causing hydroxy radicals as a biproduct of melanin production. Rieske complex, the iron complex of Complex I or NADH-CoQ10 in mitochondrial respiration is effected. It binds with the P-glycoprotein that triggers a MAP cascade and the formation of MAP1 and MAP2 that are part of Lewy Bodies. The P Glycoprotein also activates RAS. RAS causes cells to proliferate over and over in cancer. It is involved in Lewy Body formation. P-glycoprotein also binds with phosphatidylcholine and phosphatidylethanolamine. Choline is the primary component of acetylcholine that makes you tremor. It functions with inositol which binds with the D2 dopamine receptors through phosphoinositide hydrolysis. Dimethylamine binds with trentoin, 13-cis-retinoic acid, that causes craniofacial birth defects, like Parkinsonian blue-yellow colorblindness and olfactory dysfunction, and 13-cis-retinoic acid binds with Bcr or breakpoint clusters that govern the environmental cause of the genetic illness Chronic myelogenous leukemia. Dimethylamine inhibits Retinoid X and Retinoid X mutant mice have Parkinsons locomotion. It is in the anti-knock additive of jet fuel and airline stewardesses in Alaska, Canada, and Australia have suits against the airlines for getting Parkinsons disease. Amantadine is from a fungus, it is an antiviral against the influenza virus whose immunodominant peptide is 155kD. SHIP 2 , a 155kD phosphatidylinositol, 3,4,5-triphosphate is associated with the breakpoint cluster of Chronic myelogenous leukemia. Wortmannin is an antifungal that inhibits phosphatidylinositol 3,4,5-triphosphate that is involved in Parkinsonian phosphoinositide hydrolysis. Chloroquine is 155kD to 170kD. Ethoxyquin (Trimethylquinoline) would increase isoquinone (IQ) MAO is concentrated in the dopaminergic neuronal mitochondria and catalyzes NMTIQ to NMIQ+ in the substantia nigra. Benzyltetrahydroisoquinolines are linked to Parkinsons, actually, progressive supranuclear palsy. The Bacillus Thuringiensis Cry1A delta-endotoxin aminopeptidase 170kD is used to kill mosquitoes. The endotoxin has a cross-linking determinant typical of a cleaved glycosyl-phosphatidylinositol anchor. I think it caused encephalitis Parkinsons. Just my opinion. [log in to unmask]