Hi Don-- I don't know, but suggest you ask your pharmacist to check for possible interactions--tell him/her everything you are taking--should be able to help. > Hi from W.PA, I'm currently on 2 Amantadine-100mg, 2.5 Sinemet >CR- 50/200, 1 Sinemet- 25/100 daily. On Monday, I'm scheduled for the >extraction of 2 teeth and the dentist has prescribed Vicodan E. S. for >pain. We don't have access to a PDR. Does anyone know if there will >be any adverse reactions with my meds? Thanks. Don Camilla Flintermann, CG for Peter 81/70/55 Oxford, Ohio http://www.newcountry.nu/pd/members/camilla/one.htm <[log in to unmask]> "Ask me about the CARE list for Caregivers of Parkinsonians ! "