Greetings...I have not been reading mail since MONDAY a.m. and had not planned to return to the list until Friday night. But I think I need some advice! IN the spring my mother was taken off one drug (bradic...can't remember the name, sorry) and put on Requip in staged doses. She has had her dosage increased over the summer...One more visit to her neurologist should bring the dosage up to what it should be for her. It has been hard for her body to adjust physically, but a few weeks ago her eyes were looking brighter, she had better balance when walking, and claimed one or two 'normal days'. Since Sunday, she has taken a huge turn for the worse...She is depressed (asked me to check into living wills), walking is very difficult for her without some kind of assistance and of course her confidence is gone. She claims hallucinations (but also has cateracts which may be contributing) and sleeplessness. Even her hair has greyed a little more (she's 78, was diagnosed in 91). There is more to tell but I am wondering how to help her with the timing of her medications to get their optimal effect (I have surfed to Brian Collins' website...a wonderful resource!...but I don't know if she will understand the charting method of timing drug intake bacause I don't yet. I will try to get her back to the neurologist today if he will see her, but in the meantime, any suggestions? Alos, any feedback on getting used to REQUIIP initially from anyone? I would also be interested in knowing more about CARE (how to subscribe, etc.). Thanks immensely! Joan U.