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Debby Interesting the replies so far to my original inquiry about brains turning to "mush" and people on Mirapex. About getting older I don't doubt that has something to do with it. I am 71 and was given the good news that I had PD about 5 - 6 years ago. I honestly can't recall how long I have been on Mirapex but it has to be around 2 years also. I also take Sinimet CR 25/100 five times a day and Tasmar 100 three times a day. Great stuff that Tasmar even though I have to have blood tests every two weeks. Hope I get more replies. I will take them to my neurologist next trip. Eldon Green Tampa Bay, Florida