Dear List:
This posting disturbs me. I hope that people don't
try such experimentation on their own. Before I decided to post a
response, I went to Dr. Lieberman and asked what he thought about this and he
reinforced what I already thought. He said that he was not sure how
effective the medication would be when delivered in this fashion. I asked
about potential sinus infections from this as well and he said that yes,
infections could occur, but not only that, the levodopa can be very caustic to
the nasal mucosa, burn, and may end up destroying the mucosa. This could
potentially lead to a perforation of the nasal septum, and as any of us can
imagine, that would be very painful.
Before any members of the list prepare their medications
this way, please discuss it with your doctor. I know it is
desirable to bypass all the problems associated with taking Sinemet orally, but
I would hate to think that someone ends up with other problems because they took
their medication in an un-intended, unconventional route. Please let your
doctors practice medicine...they are the ones with knowledge and are educated to
do so. If you are uncomfortable with what your doctor orders or with the
treatment that is recommended, it's time to seek treatment from another doctor.
Sincerely,
Bonnie Cunningham
NPF
Date: Tue, 24 Aug 1999 14:32:14
-0400
From: "Patrick J. Martin" <[log in to unmask]>
Subject:
Nasl spray for levodopa
I hope this is of interest to those of us who are
longtime users of Ldopa=
Subject : Ldopa - up your nose
325
milligrams sodium chloride, usp crystals
50 milligrams sodium
ascorbate , usp crystals
100 milligrams levodopa, usp crystals
50
milliliters distilled water
1 milliliter glycerol, usp liquid
Mix these
ingredients until solution is clear. Load into two metering =
nasal
sprayers. I have used sprayers ranging from 0.1 milliliter/spray =
to
0.3 milliliter/spray. I have used doses from 1 spray/nostril to 3
spr=
ays per nostril -- giving my skull circulating system access to levodopa
=
quantities ranging from 0.2 milligrams to 1.8 milligrams
Why -- these snorts give me quick, non-intestinal tract
access to my
beloved dopamine precursor that overrides the food amino
acids that =
are competing with it ; eliminate some carbidopa from my
drug mix; and =
provide some supplemental levodopa in times of
stress.
May God be with you.
You can call me at 408-286-3967 until
about 1800 hours or you drop me a n=
ote at: 1680 University Avenue
=
San Jose, CA 95126
Zymurgist1
<Patrick J Martin>