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Hi, I'm a newbie to the list and to PD. I've been on Sinemet for about three months. I was supposed to be on 25/100 3x a day, but the pharmacy made a mistake and filled the prescription with 25/250! I was really nauseated after taking the pills. (Ate soda crackers too, which helped somewhat.) I didn't discover the pharmacy error until I went back for a refill, and got the 25/100's! Taking the right strength of Sinemet has really helped. I feel almost normal (whatever normal is, lol) I've also been taking Eldepryl now for about a month. I'm able to walk better, except I've been having problems with pain in my left leg from my hip to my ankle. Some nights I can't sleep because I can't get comfortable. Has anyone else experienced this? My neuro said after he resolved the other problems he'd deal with this. He thought the meds might help, and they have to some degree. I have questions about diet too. Nothing was said about the problems of eating protein with Sinemet but I did hear about this from another PD friend. Wondering if there's something I should know also about Eldepryl. Appreciate any help, Barbara 61/61/? At 11:36 PM 8/31/99 EDT, you wrote: > Hi, All ! >Janet and Erwin have been discussing the side effect,nausea,at the >introduction of Sinemet. >It is my understanding that the carbadopa part of Sinemet is what keeps the >levodopa from producing systemic side effects, such as nausea. >Back in1984 when I first started Sinemet 10/100, I had full-blown nausea >after each dose. To ease the nausea I devourred afew soda crackers following >the med ....It was some relief. >When I finally advanced to 25/100 Sinemet I had no more nausea. > >That's just my experience..I'm not a professional....Ask your doctor ! > [log in to unmask] )Mary Manfredi) fourscore plus two/dx 15 > >