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Veronica.... Without going into my entire PD history (25 years with the steeeeenkin' disease), I've had complete frequency-urge--relief from for the past year after a complete urological check-up (to make sure there was nothing else than the PD causing the problem). The urologist prescribed Ditropan PLUS Imipramine. The prescribed dosage was originally Ditropan 3 times daily, with the Imipramine once daily at bedtime, however, I've ended up taking 1/2 tablet Ditropan twice daily, and the Imipramine once daily at bedtime. I cannot tell you what a relief it's been to me to be *NORMAL* once again! But unfortunately the drugs don't cure the root of the problem - the pills are a life-time thing according to the urologist. (so what ELSE is new?) <sigh> Good luck m'dear.... I empathize with you. Barb Mallut [log in to unmask] --Original Message----- From: John Levin <[log in to unmask]> To: [log in to unmask] <[log in to unmask]> Date: Monday, September 06, 1999 3:34 AM Subject: Help wanted >I have been lurking on the list for some time. My Husband a retired MD has >been a member of the list for the same time. I am a PWP aged 63 who was >diagnosed approx. 7 yrs ago. I am well controlled; I take Sinemet CR 100mg x >4 and Permax 250 x 3 > >My problem is with my bladder. Frequency has been a slight problem all of my >adult life, but it is getting much worse - frequency, urgency (no >incontinence) every 1/2 hour. I am supposed to be going on holidays at the >end of the month and I'm very concerned about coping. > >I have been to a couple of Urologists. Here is a list of treatments I've tried: > 1) Fluoroscopic exam. of bladder indicating a small sensitive bladder. > 2) Stretching under general anaesthetic - wonderful result which >lasted one week. > 3) Ditropan 2.5 mg x 3 - slight improvement. > 4) Tolteradine (new drug trial) - no use. > 5) Phsiotherapist - electrodes to lower back - no use. >A final suggestion has been "Interstim Continence Control" Therapy. An >implant which stimulates nerves in the sacrum. This sounds very drastic but >apparently has 65% success rate. Yesterday I took valium which seemed to help. >Has anyone any advice that can help me. >Veronica.