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PD researchers think that the glutamate family of neurotransmitters, particularly N-Methyl-D-Aspartate (NMDA), is harmful to the neurons whose failure causes PD. So they are testing NMDA antagonists such as amantadine (Symmetrel) and riluzole (Rilutek) in hopes they will help alleviate the symptoms of PD. Now here comes a report in this week's Nature, also picked up by Science News, that mice genetically altered to have extra NMDA are demonstrably smarter than ordinary mice (They learn, adapt, and remember better). It's cautiously foreseen as an IQ-gene for people! Conversely, it boils down to this: If you have PD, it may be because you aren't dumb. Will we someday get to choose? Cheers, Joe -- J. R. Bruman (818) 789-3694 3527 Cody Road Sherman Oaks, CA 91403-5013